Sandra Castillo is a Junior PI in the Group of Dr. Mariona Graupera at the Josep Carreras Leukaemia Research Institute. She obtained her B.Sc. in Biology at the Universidad de Navarra followed by a Ph.D. in cancer genetics from Universitat de Barcelona where she studied new genes involved in cancer development at the laboratory of Dr. Montse Sanchez-Cespedes. In 2012 she joined the laboratory of Prof. Bart Vanhaesebroeck in London to study oncogenic PI3K signalling in cancer and rare syndromes. There, she discovered new genetic events in vascular malformations and provided preclinical models and proof of concept for the use of PI3K pathway inhibitors for the treatment of these diseases. Back in Barcelona, in 2017 she joined the laboratory of Dr. Mariona Graupera with a Marie Curie Fellowship and she has recently obtained independent funding as principal investigator from la Caixa Junior Leader Fellowship to develop research lines aimed at the understanding of rare genetic syndromes caused by oncogenic signalling.