Institut de Recerca contra la Leucèmia Josep Carreras, Spain
Mariona Graupera is a group leader at the Josep Carreras Leukaemia Research Institute.
She obtained her PhD in Biochemistry from the University of Barcelona, focusing on the pathobiology of endothelial cells in liver cirrhosis. She carried out postdoctoral studies with Bart Vanhaesebroeck first at the Ludwig Institute for Cancer Research and later the Barts Institute of Cancer, London where she was involved in characterizing the physiological role of class I PI3K isoforms. In particular, Mariona Graupera unravelled the importance of being selective in angiogenesis during development. In 2009 she had the opportunity to create a multidisciplinary laboratory devoted to study PI3K/PTEN signalling in physiopathological angiogenesis at IDIBELL with a Ramon y Cajal position. In February 2021 Mariona Graupera was appointed the Group Leader of the Endothelial Pathobiology and Microenvironment Group to the Josep Carreras Leukaemia Research Institute where she combines her passion for biomedical research and vascular biology with the training of students and postdocs. Her group investigates the role of blood vessels in disease towards the development of therapeutic strategies to target the vascular compartment.
Figueiredo AM, Villacampa P, Diéguez-Hurtado R, José Lozano J, Kobialka P, Cortazar AR, Martinez-Romero A, Angulo-Urarte A, Franco CA, Claret M, Aransay AM, Adams RH, Carracedo A, Graupera M.
Circulation. 2020 Aug 18;142(7):688-704.
Hermanova I, Zúñiga-García P, Caro-Maldonado A, Fernandez-Ruiz S, Salvador F, Martín-Martín N, Zabala-Letona A, Nuñez-Olle M, Torrano V, Camacho L, Lizcano JM, Talamillo A, Carreira S, Gurel B, Cortazar AR, Guiu M, López JI, Martinez-Romero A, Astobiza I, Valcarcel-Jimenez L, Lorente M, Arruabarrena-Aristorena A, Velasco G, Gomez-Muñoz A, Suárez-Cabrera C, Lodewijk I, Flores JM, Sutherland JD, Barrio R, de Bono JS, Paramio JM, Trka J, Graupera M, Gomis RR, Carracedo A.
J Exp Med. 2020 Jun 1;217(6):e20191787.
Sandra D Castillo, Elena Tzouanacou, May Zaw-Thin, Inma M Berenjeno, Victoria E R Parker, Iñigo Chivite, Maria Milà-Guasch, Wayne Pearce, Isabelle Solomon, Ana Angulo-Urarte, Ana M Figueiredo, Robert E Dewhurst, Rachel G Knox, Graeme R Clark , Cheryl L Scudamore, Adam Badar, Tammy L Kalber, Julie Foster, Daniel J Stuckey, Anna L David , Wayne A Phillips, Mark F Lythgoe, Valerie Wilson, Robert K Semple, Neil J Sebire, Veronica A Kinsler, Mariona Graupera, Bart Vanhaesebroeck
Sci Transl Med. 2016 Mar 30;8(332):332ra43.
Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, Pandolfi PP, Bigas A, Carracedo A, Gerhardt H, Graupera M.
Nat Commun. 2015 Jul 31;6:7935.
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