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Guillaume Canaud


Université de Paris, France

Guillaume Canaud is a MD, PhD and the Chief of the Overgrowth syndromes and vascular anomalies Unit at Necker Enfants Malades Hospital in Paris. He did his medical school in Montpellier and moved to Paris in 2002 to perform his Residency in Nephrology (2002 to 2007). He became Senior Resident in the Renal Division of Necker (Prof. Legendre) from 2007 to 2012. Concurrently, he spent four years from to 2008 to 2012 in the laboratory of Dr. Fabiola Terzi (INSERM U1151, Necker Hospital) to achieve his PhD degree in molecular and cellular biology. Then, he joined the Joseph Bonventre’s Laboratory (Harvard Medical School, Boston, USA) from 2012 to 2014 to achieve a postdoc.

Guillaume obtained several grants including 3 European Research Council (Starting grant in 2015, Proof of Concept in 2016 and Consolidator in 2020). With his group they are exploring the role PI3KCA in overgrowth syndromes and vascular anomalies.


  • Targeted therapy in patients with PIK3CA-related overgrowth syndrome.
    Venot Q, Blanc T, Rabia SH, Berteloot L, Ladraa S, Duong JP, Blanc E, Johnson SC, Hoguin C, Boccara O, Sarnacki S, Boddaert N, Pannier S, Martinez F, Magassa S, Yamaguchi J, Knebelmann B, Merville P, Grenier N, Joly D, Cormier-Daire V, Michot C, Bole-Feysot C, Picard A, Soupre V, Lyonnet S, Sadoine J, Slimani L, Chaussain C, Laroche-Raynaud C, Guibaud L, Broissand C, Amiel J, Legendre C, Terzi F, Canaud G. Nature. 2018 Jun;558(7711):540-546.